May 23, 2025 - By :

Gallstone Induced Problems Vs Acid Reflux – How to Know the Difference ?

By Dr. Tapas Mishra | Senior Consultant – Advanced Laparoscopic GI & Bariatric Surgery

If you’ve experienced a burning sensation in your chest or a sharp pain in your upper abdomen, you might wonder: Is this Acid Reflux or something more serious, like a Gallbladder infection

Though both affect the digestive system, they are very different in cause, symptoms, and treatment. Recognizing the signs early can help you take the right steps for relief.

What is a Gallbladder infection or cholecystitis

A Gallbladder infection occurs when gallstones block the normal passage of gall bladder to common bile duct , causing a buildup of pressure and inflammation. It often occurs spontaneously or after a heavy or fatty meal and can last for several hours.

Common Symptoms:

  • Sudden pain in the upper right abdomen
  • Pain that may radiate to the right shoulder or back
  • Nausea and vomiting
  • Pain lasting 30 minutes to several hours
  • No relief from over-the-counter antacids

The pain tends to come on quickly,   is colicky and doesn’t improve with rest or changes in posture. In some cases, fever or chills may also develop, signaling a more serious issue.

What is Acid Reflux?

Acid reflux, or Gastro Esophageal Reflux Disease (GERD), occurs when stomach acid flows back into the Esophagus. This backward flow causes irritation, often after eating or when lying down.

Typical Symptoms:

  • Burning sensation in the chest (heartburn)
  • A sour or bitter taste in the mouth
  • Burping, bloating, and gas
  • Discomfort that worsens when bending over or lying flat
  • Relief with antacids or acid blockers

Unlike an attack of cholecystitis, acid reflux is usually chronic and recurrent  and can occur daily or weekly, depending on diet and lifestyle.

Key Differences at a Glance:

IssueGallbladder infectionAcid Reflux
Pain AreaUpper right abdomenChest/upper abdomen
TriggerFatty/heavy mealsSpicy food, lying down
Duration30 mins to hoursShort episodes, recurring
Antacids Help?NoOften yes

 

What You Can Do ?

If you’re unsure which condition you’re experiencing, pay attention to the type, location, and timing of your symptoms. While acid reflux can often be managed with lifestyle changes and medications, gallbladder issues may require medical imaging or surgical intervention.

Persistent or intense symptoms should never be ignored. If pain worsens or is accompanied by fever, seek prompt surgeon attention to avoid complications.